Notes from the trenches on AI engineering, LLM apps, and the full-stack work that holds it all together.
A narrow AI workflow audit beats a vague AI strategy deck. Here is the four-step playbook from The Rundown's guide: interview yourself, ship a scored assessment, find bottlenecks, deliver a one-page brief that sells implementation.
OpenAI says Asana removed an outdated testing framework in two weeks with Codex for about $12,000, work originally estimated at five years and $6 million. What that number actually signals for legacy migration projects.
Astromech spun out of de-extinction startup Colossal with $20M fresh funding at a $3.8B valuation. The pitch is a biological operating system that predicts evolutionary change from genomic and ancestral data.
Bankrupt Spirit Airlines' corporate archive includes 100M emails and crew records. Flight attendants blocked Google's purchase while Micro1 offered $12.5M. The fight is over who owns the exhaust of a dead company.
Intismeran Autogene plus Keytruda beat pembrolizumab alone in 1,137 resected melanoma patients. It is the first Phase 3 win for an mRNA cancer therapy and the first individualized neoantigen shot to beat active standard of care.
Spotify founder Daniel Ek's Neko Health is bringing its 60-minute full-body scan clinic to SoHo on September 24. More than 25,000 New Yorkers already queued for a $499 radiation-free checkup.
OpenAI shipped a plugin for Apple Messages so ChatGPT can search, read, and send texts from ChatGPT, Codex, and Work. Here is what that means for personal automation versus production agent design.
Salesforce launched Slack Code: dedicated code channels where AI agents write software while PMs and engineers steer in the open. Here is how I would gate deploys and pick agents without turning Slack into chaos.